Kristin Beebe : rechercher sur Z-Library

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Articles (36)
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Comparison of oil and egg tempera paint systems using time-of-flight secondary ion mass spectrometry

Voras, Zachary E., deGhetaldi, Kristin, Baade, Brian, Gordon, Eric, Gates, Glenn, Beebe, Thomas P.

Journal:

Studies in Conservation

Année:

2016

Langue:

english

Fichier:

PDF, 3.27 MB

english, 2016

Divergent Synthesis of a Pochonin Library Targeting HSP90 and In Vivo Efficacy of an Identified Inhibitor

Sofia Barluenga, Cuihua Wang, Jean-Gonzague Fontaine, Kaïss Aouadi, Kristin Beebe, Shinji Tsutsumi, Len Neckers, Nicolas Winssinger

Journal:

Angewandte Chemie

Année:

2008

Langue:

english

Fichier:

PDF, 563 KB

english, 2008

Divergent Synthesis of a Pochonin Library Targeting HSP90 and In Vivo Efficacy of an Identified Inhibitor

Sofia Barluenga, Cuihua Wang, Jean-Gonzague Fontaine, Kaïss Aouadi, Kristin Beebe, Shinji Tsutsumi, Len Neckers, Nicolas Winssinger

Journal:

Angewandte Chemie International Edition

Année:

2008

Langue:

english

Fichier:

PDF, 563 KB

english, 2008

Inhibition of HSP90 with Pochoximes: SAR and Structure-Based Insights

Sofia Barluenga, Jean-Gonzague Fontaine, Cuihua Wang, Kais Aouadi, Ruihong Chen, Kristin Beebe, Len Neckers, Nicolas Winssinger

Journal:

ChemBioChem

Année:

2009

Langue:

english

Fichier:

PDF, 640 KB

english, 2009

Concise Modular Asymmetric Synthesis of Deguelin, Tephrosin and Investigation into Their Mode of Action

José Garcia, Sofia Barluenga, Kristin Beebe, Len Neckers, Nicolas Winssinger

Journal:

Chemistry - A European Journal

Année:

2010

Langue:

english

Fichier:

PDF, 384 KB

english, 2010

Calcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cells

Meghna U. Naik, Ngoc T. Pham, Kristin Beebe, Wei Dai, Ulhas P. Naik

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 699 KB

english, 2011

Synthesis and evaluation of 8,9-amido analogs of geldanamycin

Merritt B. Andrus, Yong Wong, Jing Liu, Kristin Beebe, Leonard M. Neckers

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 397 KB

english, 2009

Azaspirene, a fungal product, inhibits angiogenesis by blocking Raf-1 activation

Yukihiro Asami, Hideaki Kakeya, Yusuke Komi, Soichi Kojima, Kiyohiro Nishikawa, Kristin Beebe, Len Neckers, Hiroyuki Osada

Journal:

Cancer Science

Année:

2008

Langue:

english

Fichier:

PDF, 381 KB

english, 2008

An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Bradley T. Scroggins, Kenneth Robzyk, Dongxia Wang, Monica G. Marcu, Shinji Tsutsumi, Kristin Beebe, Robert J. Cotter, Sara Felts, David Toft, Larry Karnitz, Neal Rosen, Len Neckers

Journal:

Molecular Cell

Année:

2007

Langue:

english

Fichier:

PDF, 815 KB

english, 2007

Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function

Mehdi Mollapour, Shinji Tsutsumi, Alison C. Donnelly, Kristin Beebe, Mari J. Tokita, Min-Jung Lee, Sunmin Lee, Giulia Morra, Dimitra Bourboulia, Bradley T. Scroggins, Giorgio Colombo, Brian S. Blagg,

Journal:

Molecular Cell

Année:

2010

Langue:

english

Fichier:

PDF, 821 KB

english, 2010

Threonine 22 Phosphorylation Attenuates Hsp90 Interaction with Cochaperones and Affects Its Chaperone Activity

Mehdi Mollapour, Shinji Tsutsumi, Andrew W. Truman, Wanping Xu, Cara K. Vaughan, Kristin Beebe, Anna Konstantinova, Srinivas Vourganti, Barry Panaretou, Peter W. Piper, Jane B. Trepel, Chrisostomos Pr

Journal:

Molecular Cell

Année:

2011

Langue:

english

Fichier:

PDF, 930 KB

english, 2011

Dynamic Tyrosine Phosphorylation Modulates Cycling of the HSP90-P50CDC37-AHA1 Chaperone Machine

Xu, Wanping, Mollapour, Mehdi, Prodromou, Chrisostomos, Wang, Suiquan, Scroggins, Bradley T., Palchick, Zach, Beebe, Kristin, Siderius, Marco, Lee, Min-Jung, Couvillon, Anthony, Trepel, Jane B., Miyat

Journal:

Molecular Cell

Année:

2012

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2012

Synthesis and Structure–Activity Relationship Studies of Novel Dihydropyridones as Androgen Receptor Modulators

Pepe, Antonella, Pamment, Michael, Kim, Yeong Sang, Lee, Sunmin, Lee, Min-Jung, Beebe, Kristin, Filikov, Anton, Neckers, Len, Trepel, Jane B., Malhotra, Sanjay V.

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2013

Asymmetric Hsp90 N Domain SUMOylation Recruits Aha1 and ATP-Competitive Inhibitors

Mollapour, Mehdi, Bourboulia, Dimitra, Beebe, Kristin, Woodford, Mark R., Polier, Sigrun, Hoang, Anthony, Chelluri, Raju, Li, Yu, Guo, Ailan, Lee, Min-Jung, Fotooh-Abadi, Elham, Khan, Sahar, Prince, T

Journal:

Molecular Cell

Année:

2014

Langue:

english

Fichier:

PDF, 2.85 MB

english, 2014

Isolation of Hybridoma Forming Cells From Immune Spleens by Unit Gravity Sedimentation

KUUS-REICHEL, KRISTINE, BEEBE, AMY, KNOTT, CHRISTINE

Journal:

Hybridoma

Année:

1991

Langue:

english

Fichier:

PDF, 983 KB

english, 1991

Production of IgG Monoclonal Antibodies to the Tumor-Associated Antigen, CA-195

KUUS-REICHEL, KRISTINE, KNOTT, CHRISTINE L., McCORMACK, ROBERT T., GUIDO, MARK S., BEEBE, AMY

Journal:

Hybridoma

Année:

1994

Langue:

english

Fichier:

PDF, 937 KB

english, 1994

Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

Moulick, Kamalika, Ahn, James H, Zong, Hongliang, Rodina, Anna, Cerchietti, Leandro, Gomes DaGama, Erica M, Caldas-Lopes, Eloisi, Beebe, Kristin, Perna, Fabiana, Hatzi, Katerina, Vu, Ly P, Zhao, Xinya

Journal:

Nature Chemical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 841 KB

english, 2011

Computational Polypharmacology Analysis of the Heat Shock Protein 90 Interactome

Anighoro, Andrew, Stumpfe, Dagmar, Heikamp, Kathrin, Beebe, Kristin, Neckers, Leonard M., Bajorath, Jürgen, Rastelli, Giulio

Journal:

Journal of Chemical Information and Modeling

Année:

2015

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2015

Regulation and function of the human HSP90AA1 gene

Zuehlke, Abbey D., Beebe, Kristin, Neckers, Len, Prince, Thomas

Journal:

Gene

Année:

2015

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2015

Combined HSP90 and kinase inhibitor therapy: Insights from The Cancer Genome Atlas

Schwartz, Harvey, Scroggins, Brad, Zuehlke, Abbey, Kijima, Toshiki, Beebe, Kristin, Mishra, Alok, Neckers, Len, Prince, Thomas

Journal:

Cell Stress and Chaperones

Année:

2015

Langue:

english

Fichier:

PDF, 1.90 MB

english, 2015

Effects of an opioid (proenkephalin) polymorphism on neural response to errors in health and cocaine use disorder

Moeller, Scott J., Beebe-Wang, Nicasia, Schneider, Kristin E., Konova, Anna B., Parvaz, Muhammad A., Alia-Klein, Nelly, Hurd, Yasmin L., Goldstein, Rita Z.

Journal:

Behavioural Brain Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2015

Impact of heat-shock protein 90 on cancer metastasis

Tsutsumi, Shinji, Beebe, Kristin, Neckers, Len

Journal:

Future Oncology

Année:

2009

Langue:

english

Fichier:

PDF, 663 KB

english, 2009

ToF–SIMS imaging of molecular-level alteration mechanisms inLe Bonheur de vivreby Henri Matisse

Voras, Zachary E., deGhetaldi, Kristin, Wiggins, Marcie B., Buckley, Barbara, Baade, Brian, Mass, Jennifer L., Beebe, Thomas P.

Journal:

Applied Physics A: Materials Science & Processing

Année:

2015

Langue:

english

Fichier:

PDF, 3.59 MB

english, 2015

Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors

Woodford, Mark R., Truman, Andrew W., Dunn, Diana M., Jensen, Sandra M., Cotran, Richard, Bullard, Renee, Abouelleil, Mourad, Beebe, Kristin, Wolfgeher, Donald, Wierzbicki, Sara, Post, Dawn E., Caza,

Journal:

Cell Reports

Année:

2016

Langue:

english

Fichier:

PDF, 4.03 MB

english, 2016

Low-penetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras

Park, Yoonsoo, Kubo, Akihito, Komiya, Takefumi, Coxon, Amy, Beebe, Kristin, Neckers, Len, Meltzer, Paul S., Kaye, Frederic J.

Journal:

Cell Cycle

Année:

2008

Langue:

english

Fichier:

PDF, 685 KB

english, 2008

Is Dantrolene Safe to Administer in Sepsis?

Beebe, David S., Belani, Kumar G., Tuohy, Stephen E., Sweeney, Michael F., Gillingham, Kristin, Komanduri, Vijaya, Palahniuk, Richard J.

Journal:

Anesthesia & Analgesia

Année:

1991

Langue:

english

Fichier:

PDF, 567 KB

english, 1991

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Kang, Byoung Heon, Plescia, Janet, Song, Ho Young, Meli, Massimiliano, Colombo, Giorgio, Beebe, Kristin, Scroggins, Bradley, Neckers, Len, Altieri, Dario C

Journal:

Journal of Clinical Investigation

Année:

2009

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2009

In-depth examination and analysis of Domenico Cresti's oil on wall paintings in Santa Maria della pace in Rome

de Ghetaldi, Kristin, Wiggins, Marcie B., Bertorello, Carla, Voras, Zachary, Norbutus, Amanda, Beebe Jr, Thomas P., Baade, Brian

Journal:

Journal of Cultural Heritage

Année:

2017

Langue:

english

Fichier:

PDF, 3.16 MB

english, 2017

An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans

Zuehlke, Abbey D., Reidy, Michael, Lin, Coney, LaPointe, Paul, Alsomairy, Sarah, Lee, D. Joshua, Rivera-Marquez, Genesis M., Beebe, Kristin, Prince, Thomas, Lee, Sunmin, Trepel, Jane B., Xu, Wanping,

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2017

Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation

Bachman, Ashleigh B., Keramisanou, Dimitra, Xu, Wanping, Beebe, Kristin, Moses, Michael A., Vasantha Kumar, M. V., Gray, Geoffrey, Noor, Radwan Ebna, van der Vaart, Arjan, Neckers, Len, Gelis, Ioannis

Journal:

Nature Communications

Année:

2018

Langue:

english

Fichier:

PDF, 2.25 MB

english, 2018

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation

Kijima, Toshiki, Prince, Thomas L., Tigue, Megan L., Yim, Kendrick H., Schwartz, Harvey, Beebe, Kristin, Lee, Sunmin, Budzynski, Marek A., Williams, Heinric, Trepel, Jane B., Sistonen, Lea, Calderwood

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2018

Targeting the Hsp40/Hsp70 chaperone axis as a novel strategy to treat castration-resistant prostate cancer

Moses, Michael A., Kim, Yeong Sang, Rivera-Marquez, Genesis M, Oshima, Nobu, Watson, Matthew J, Beebe, Kristin, Wells, Catherine, Lee, Sunmin, Zuehlke, Abbey D, Shao, Hao, Bingman, William E, Kumar, V

Journal:

Cancer Research

Année:

2018

Langue:

english

Fichier:

PDF, 16.72 MB

english, 2018

Surface Analysis of Fine Art Paintings: Studying Degradation Mechanisms with a Systematic Approach

Beebe, Thomas P, Voras, Zachary, de Gheraldi, Kristin, Mass, Jennifer

Journal:

Microscopy and Microanalysis

Année:

2018

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2018

Obesity and risk factors for the metabolic syndrome among low-income, urban, African American schoolchildren: the rule rather than the exception?

Braunschweig, Carol L, Gomez, Sandra, Liang, Huifang, Tomey, Kristin, Doerfler, Bethany, Wang, Youfa, Beebe, Chris, Lipton, Rebecca

Journal:

American Journal of Clinical Nutrition

Année:

2005

Langue:

english

Fichier:

PDF, 93 KB

english, 2005

Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1

Xu, Wanping, Beebe, Kristin, Chavez, Juan D., Boysen, Marta, Lu, YinYing, Zuehlke, Abbey D., Keramisanou, Dimitra, Trepel, Jane B., Prodromou, Christosomos, Mayer, Matthias P., Bruce, James E., Gelis,

Journal:

Nature Communications

Année:

2019

Langue:

english

Fichier:

PDF, 3.22 MB

english, 2019

Phase 1 study of the HSP90 inhibitor onalespib in combination with AT7519, a pan-CDK inhibitor, in patients with advanced solid tumors

Do, Khanh T., OâSullivan Coyne, Geraldine, Hays, John L., Supko, Jeffrey G., Liu, Stephen V., Beebe, Kristin, Neckers, Len, Trepel, Jane B., Lee, Min-Jung, Smyth, Tomoko, Gannon, Courtney, Hedglin,

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2020

Fichier:

PDF, 2.60 MB

2020